Publications

The food dye Tartrazine disrupts vascular formation both in zebrafish larvea and in human primary endothelial cells.

Thanh DD, Bich-Ngoc N, Paques C, Christian A, Herkenne S, Struman I, Muller M. Sci Rep. 2024 Dec5; 14(1):30367

Non-canonical role for the BAF complex subunit DPF3 in mitosis and ciliogenesis.

Verrillo G, Obeid AM, Genco A, Scrofani J, Orange F, Hanache S, Mignon J, Leyder T, Michaux C, Kempeneers C, Bricmont N, Herkenne S, Vernos I, Martin M, Mottet D.J Cell Sci. 2024 May 1;137(9)

Activation of Ca²⁺ phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy in flies.

Marchesan E, Nardin A, Mauri S, Bernardo G, Chander V, Di Paola S, Chinellato M, von Stockum S, Chakraborty J, Herkenne S, Basso V, Schrepfer E, Marin O, Cendron L, Medina DL, Scorrano L, Ziviani E.Cell Death Differ. 2024 Feb;31(2):217-238

Endothelial extracellular vesicles promote tumour growth by tumour-associated macrophage reprogramming.

Njock MS, O'Grady T, Nivelles O, Lion M, Jacques S, Cambier M, Herkenne S, Muller F, Christian A, Remacle C, Guiot J, Rahmouni S, Dequiedt F, Struman I.J Extracell Vesicles. 2022 Jun;11(6):e12228.

Inhibition of the mitochondrial protein Opa1 curtails breast cancer growth.

Zamberlan M, Boeckx A, Muller F, Vinelli F, Ek O, Vianello C, Coart E, Shibata K, Christian A, Grespi F, Giacomello M, Struman I, Scorrano L, Herkenne S.J Exp Clin Cancer Res. 2022 Mar 12;41(1):95.

Extracellular Vesicles Mediate Communication between Endothelial and Vascular Smooth Muscle Cells.

Fontaine M, Herkenne S, Ek O, Paquot A, Boeckx A, Paques C, Nivelles O, Thiry M, Struman I.Int J Mol Sci. 2021 Dec 28;23(1):331.

The mitochondrial protein Opa1 promotes adipocyte browning that is dependent on urea cycle metabolites.

Bean C, Audano M, Varanita T, Favaretto F, Medaglia M, Gerdol M, Pernas L, Stasi F, Giacomello M, Herkenne S, Muniandy M, Heinonen S, Cazaly E, Ollikainen M, Milan G, Pallavicini A, Pietiläinen KH, Vettor R, Mitro N, Scorrano L.Nat Metab. 2021 Dec;3(12):1633-1647.

OPA1, a new mitochondrial target in cancer therapy.

Herkenne S, Scorrano L.Aging (Albany NY). 2020 Nov 13;12(21):20931-20933.

Inhibition of autophagy curtails visual loss in a model of autosomal dominant optic atrophy.

Zaninello M, Palikaras K, Naon D, Iwata K, Herkenne S, Quintana-Cabrera R, Semenzato M, Grespi F, Ross-Cisneros FN, Carelli V, Sadun AA, Tavernarakis N, Scorrano L.Nat Commun. 2020 Aug 12;11(1):4029

CD73⁺ extracellular vesicles inhibit angiogenesis through adenosine A_2B receptor signalling.

Angioni R, Liboni C, Herkenne S, Sánchez-Rodríguez R, Borile G, Marcuzzi E, Calì B, Muraca M, Viola A.J Extracell Vesicles. 2020 May 4;9(1):1757900.

Developmental and Tumor Angiogenesis Requires the Mitochondria-Shaping Protein Opa1.

Herkenne S, Ek O, Zamberlan M, Pellattiero A, Chergova M, Chivite I, Novotná E, Rigoni G, Fonseca TB, Samardzic D, Agnellini A, Bean C, Di Benedetto G, Tiso N, Argenton F, Viola A, Soriano ME, Giacomello M, Ziviani E, Sales G, Claret M, Graupera M, Scorrano L.Cell Metab. 2020 May 5;31(5):987-1003.e8

Selected for preview:

OPA1 and Angiogenesis: Beyond the fusion function. MAX-Hinderk Schuler, Adam L. Hughes, Cell Metabolism, 2020.

The energy disruptor metformin targets mitochondrial integrity via modification of calcium flux in cancer cells.

Loubiere C, Clavel S, Gilleron J, Harisseh R, Fauconnier J, Ben-Sahra I, Kaminski L, Laurent K, Herkenne S, Lacas-Gervais S, Ambrosetti D, Alcor D, Rocchi S, Cormont M, Michiels JF, Mari B, Mazure NM, Scorrano L, Lacampagne A, Gharib A, Tanti JF, Bost F.Sci Rep. 2017 Jul 11;7(1):5040.

Reply to Filadi et al.: Does Mitofusin 2 tether or separate endoplasmic reticulum and mitochondria?

Naon D, Zaninello M, Giacomello M, Varanita T, Grespi F, Lakshminaranayan S, Serafini A, Semenzato M, Herkenne S, Hernández-Alvarez MI, Zorzano A, De Stefani D, Dorn GW 2nd, Scorrano L.Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):E2268-E2269

Critical reappraisal confirms that Mitofusin 2 is an endoplasmic reticulum-mitochondria tether.

The interaction of uPAR with VEGFR2 promotes VEGF-induced angiogenesis.

Herkenne S, Paques C, Nivelles O, Lion M, Bajou K, Pollenus T, Fontaine M, Carmeliet P, Martial JA, Nguyen NQ, Struman I.Sci Signal. 2015 Nov 17;8(403):ra117.

PAI-1 mediates the antiangiogenic and profibrinolytic effects of 16K prolactin.

Bajou K, Herkenne S, Thijssen VL, D'Amico S, Nguyen NQ, Bouché A, Tabruyn S, Srahna M, Carabin JY, Nivelles O, Paques C, Cornelissen I, Lion M, Noel A, Gils A, Vinckier S, Declerck PJ, Griffioen AW, Dewerchin M, Martial JA, Carmeliet P, Struman I.Nat Med. 2014 Jul;20(7):741-7

The antiangiogenic 16K prolactin impairs functional tumor neovascularization by inhibiting vessel maturation.

Nguyen NQ, Castermans K, Berndt S, Herkenne S, Tabruyn SP, Blacher S, Lion M, Noel A, Martial JA, Struman I.PLoS One. 2011;6(11):e27318.

The angiostatic protein 16K human prolactin significantly prevents tumor-induced lymphangiogenesis by affecting lymphatic endothelial cells.

Kinet V, Castermans K, Herkenne S, Maillard C, Blacher S, Lion M, Noël A, Martial JA, Struman I.Endocrinology. 2011 Nov;152(11):4062-71.

updated on 4/3/25