About us
The Laboratory of Molecular Angiogenesis (LAM) has a longstanding experience in the field of angiogenesis. the PI, Ingrid Struman initiated 10 years ago new project aimed at identifying and characterizing microRNAs involved in angiogenesis. Two of her studies (i.e. miR146a in PPCM5 and miR-503 in tumoral angiogenesis6) highlighted a novel mechanism of cell communication via extracellular exchange exchange of microRNAs. The PPCM paper was pioneer in the field since it was one of the first demonstration that this mechanism is involved in the etiology of a disease. She also identified microRNAs that are biomarkers of Hereditary Hemorrhagic Telangiectasia and she collaborates in a study which identified microRNA biomarkers in breast cancer.
Current work
Over the years the Lab of Ingrid Struman acquired experience in RNA (small and long RNA) profiling in exosomes. She is interested in deciphering cell communication mechanisms occurring via the exchange small/long RNA of extracellular vesicles. In parallel with basic research, she is also involved in several projects in collaboration with the clinics aiming to identify RNA/Exosomes biomarkers in breast cancer, pancreas cancer, pulmonary fibrosis…
